Tramadol HCL is a synthetic analgesic or painkiller designed to block certain brain receptors from transmitting pain sensation on our body. It is a synthetic version of codeine. Tramadol is similar to morphine as it binds itself the opioid receptors to stop the transmission of pain. It is comparable with other narcotics used for treating pain as it can also be abused. Tramadol HCL also contains antidepressant qualities through the reduction of norepinephrine and serotonin reuptake, similar to antidepressants like Effexor and Cymbalta.
For pain control, sometimes, antidepressants are used as they can help in modulating pain, the same way tramadol does. Tramadol is a mild type of norepinephrine drug that has the capacity to combine with receptor cells and create a physiological reaction with unique anti-inflammatory properties. This drug has been approved by the FDA and is prescribed for the treatment of acute or chronic pains that are from moderate to moderately severe.
Tramadol is mostly effective when it comes to treating people that have neuropathic pains (nerve pains), something that usually does not react with more classic painkillers such as morphine, hydrocodone, or oxycodone. Tramadol is almost as potent as codeine when treating pain. However, depending on affinity, results may likely differ with different individuals. There are some who will find this medication to be very effective, while some may find it to be quite ineffective in dealing with their pain. A lot of doctor’s are in the understanding that this is all due to mu-opioid agonist action which inhibits the reuptake of serotonin and norepinephrine.
Fortunately, tramadol is a well-tolerated analgesic and side effects are mostly temporary and minimal. The more common side effects involved with tramadol uptake are vertigo, vomiting, headache, nausea, and constipation. Other, but less reported side effects are sweating, diarrhea, rash, itching, and changes in visual perception. Some reports of tramadol side effect will include seizures, but often very rarely. If you are taking tramadol, remember that stopping the medication abruptly can lead to anxiety, insomnia, tremors, rigors, and even hallucinations.
The recommended dosing for tramadol HCL is 50-100mg every 4-6 hours p.r.n. and the maximum allowable dose per day is 400mg. Tramadol HCL can be taken even without food. Unlike morphine, methadone, codeine, oxycodone, hydrocodone, or Demerol, tramadol is not considered as a controlled substance. However, several U.S. states put restrictions on the purchasing of tramadol.
Tramadol is used occasionally for treating restless leg syndrome. It is also used with issues of neuropathy such as that of diabetic neuropathy. On some cases, this is given as medication for people who are undergoing depression but do not react well to other drugs or medication. Tramadol is also an effective drug in lowering blood pressure, which is of course can be the resort when other medications fail in the first place. It is found out that people who take this medication have lower blood pressure.
While the safety issue involving tramadol intake during pregnancy or when breastfeeding has not been clinically established, it is still best to avoid taking it when under these two circumstances.